CD19 anticorps

N° du produit ABIN965770

Cet anticorps Monoclonal détecte spécifiquement CD19 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD19 anticorps (ABIN965770)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CD19 anticorps

Specificité: Ni-NTA purified recombinant human CD19 expressed in E. Coli strain M15.

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot: Dilution 1: 2000- 5,000
IHC(P): Dilution 1: 100- 1: 400
IHC(F): Dilution 1: 200- 1: 400
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-CD19 (ABIN965770)

de Rie, Zeijlemaker, von dem Borne: "Inhibition, by vinca alkaloids and colchicine, of antigenic modulation induced by anti-CD19 monoclonal antibodies." dans: Leukemia research, Vol. 12, Issue 2, pp. 135-41, (1988) (PubMed).

De Rie, Zeijlemaker, Von dem Borne, Out: "Evaluation of a method of production and purification of monoclonal antibodies for clinical applications." dans: Journal of immunological methods, Vol. 102, Issue 2, pp. 187-93, (1987) (PubMed).

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet: The CD19 antigen (95kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.

ID gène: 930

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway